MAPEC

MAPEC_LIFE – Monitoring air pollution effects on children for supporting Public Health Policy – closed

Call for proposal: LIFE+2012

Role: Coordinator

Responsible for UniBS: Prof. Umberto Gelatti – Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health

Contact: umberto.gelatti@unibs.it

Start date 01/10/2014 – End date 31/12/2016

Project’s website

Abstract

MAPEC_LIFE will evaluate the links between pollutants such as PM and nitrogen oxides, and PAHs and nitroPAHs (nitro-polycyclic aromatic hydrocarbons), and their early effects. The project will then build a model for estimating the risk to children from air pollutants and other factors.

The specific objectives are:

  • To assess the concentrations of certain organic compounds (PAHs and nitroPAHs) in the air in some Italian towns;
  • To assess air mutagenicity and toxicity in the same areas, through in-vitro tests on very fine particles (PM0.5);
  • To study the relationship between the concentration of air pollutants and air mutagenicity and toxicity;
  • To investigate children’s exposure to other indoor and outdoor airborne pollutants, via a questionnaire filled in by the children’s parents;
  • To assess early effect biomarkers in oral mucosa cells from the children;
  • To carry out a risk analysis of carcinogenic effects based on environmental data;
  • To compare the results of the risk-analysis model (“expected”) with the early effect biomarkers actually found in the children (“observed”).

Expected results:

  • Completed questionnaires for 1000 children aged 6-8 years;
  • Collection of 20-45 PM0.5 air samples, and analysis of PAHs, nitroPAHs and in-vitro mutagenicity/toxicity tests on the samples;
  • Collection of 1000 samples of children’s oral mucosa cells in both summer and winter seasons, and evaluation of early effect biomarkers in the samples;
  • Preparation of risk analysis models based on environmental data;
  • An assessment of the relationship between air pollutants, air mutagenicity/toxicity, and early effect biomarkers, and an evaluation of the value of the risk analysis model for predicting early biological effects in children;
  • Construction of a global model of the risk of early biological effects in children;
  • Recommendations for measures and policies to protect children from the health effects of air pollutants.

Participants

  • UNIVERSITA’ DEGLI STUDI DI BRESCIA (Coordinator), Italy
  • COMUNE DI BRESCIA, Italy
  • CSMT Gestione s.c.a.r.l., Italy
  • UNIVERSITA’ DI PERUGIA, Italy
  • UNIVERSITA’ DI PISA, Italy
  • UNVIERSITA’ DEL SALENTO, Italy
  • UNIVERSITA’ DI TORINO, Italy

Total project costs: € 2.246,502,00 

EU contribution: € 1.112,.89,00

Overall funding assigned to UniBS: € 341.822,00

Scroll to Top