Alzheimer

Alzheimer’s Drug Discovery Foundation – Prevention beyond the pipeline

Through its Prevention beyond the pipeline Program, the ADDF seeks to support comparative effectiveness research, prevention clinical trials, and epidemiological studies that probe whether the use or choice of drugs alters the risk for dementia or cognitive decline. Duration: One year for epidemiological analyses Varies (multi-year) for clinical trials Average award: $50,000-$100,000 for epidemiological analyses […]

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Alzheimer’s Drug Discovery Foundation – Neuroimaging and CSF Biomarker development program

Given the pathological heterogeneity of Alzheimer’s disease and related dementias, new biomarkers are needed to more accurately characterize specific underlying pathophysiology. This RFP seeks to support the development of CSF and neuroimaging biomarkers for multiple contexts of use (see below) that include but are not limited to: Clearly demonstrate target engagement for novel therapeutics The

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Alzheimer’s Drug Discovery Foundation – Drug Development Program

Through its Drug Development Program the ADDF seeks to support develop therapeutics for Alzheimr’s disease and related dementias. Thsi program focuses on building preclinical evidence in animal models and on adavncing leas molecules to the clincal candidate selection stage. The propose studies shoudl have a high probability or reaching IND-enabling stuides within two years. Current

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Alzheimer’s Research UK – Target Validation Pathfinder Grant

The Target Validation Pathfinder Grant scheme provides funds for small, translational research projects that show potential for an application to the Dementia Consortium or collaboration with the ARUK Drug Discovery Alliance. The lead applicant and point of contact must be based in an academic/research institution, either in the UK or abroad. Co-applicants from small and medium enterprises

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Alzheimer, scoperta molecola che blocca la malattia

Scoperta dai ricercatori della Fondazione EBRI ‘Rita Levi-Montalcini’ una molecola che ‘ringiovanisce’ il cervello bloccando l’Alzheimer nella prima fase: è l’anticorpo A13, che ringiovanisce appunto il cervello favorendo la nascita di nuovi neuroni e contrastando così i difetti che accompagnano le fasi precoci della malattia. Lo studio, italiano, è stato effettuato su topi che, così

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Alzheimer’s Research UK – Network Cooperation

The lead applicant and point of contact must be a member of the Alzheimer’s Research UK Network. A Network cooperation application must include two or more Alzheimer’s Research UK Network Centres. It can also include researchers or institutions outside the UK. The Lead Applicant is expected to have a contract (fixed term or tenure) which covers the

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Alzheimer’s Research UK – Global Clinical Trials Fund

The Global Clinical Trials Fund covers: Studies that aim to demonstrate target engagement, Phase I or Phase II clinical trials undertaken to ascertain the potential safety and efficacy of (novel or re-purposed) drug-based interventions in human subjects Clinical trials of non-drug based, complex interventions Opportunities for research ‘add ons’ to ongoing clinical trials (e.g. validated

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Accelerating Drug Discovery for Frontotemporal Dementias

he Alzheimer’s Drug Discovery Foundation (ADDF) and The Association for Frontotemporal Degeneration (AFTD) seek to accelerate and support drug discovery for FTD and related dementias through this Request for Proposals (RFP). Priority areas for this program include: Neuroprotection Inflammation Proteostasis Mitochondria & metabolic function Vascular function Epigenetics APOE Synaptic activity and neurotransmitters Other aging target

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Alzheimer’s Research UK – Scientific conference

La Fondazione finanzia anche l’organizzazione di conferenze scientifiche con un ammontare massimo di £ 2.000. Il Lead applicant deve appartenere a un ente UK, mentre il co-applicant e il luogo della conferenza possono essere di qualsiasi parte del mondo. Le domande possono essere presentate in qualsiasi momento. In genere la risposta di finanziamento viene data dopo otto

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